Regioselective C-H Borylation of C (sp2)-H Bond
نویسندگان
چکیده
منابع مشابه
Rhodium-catalysed C(sp2)–C(sp2) bond formation via C–H/C–F activation
Fluoroalkenes represent a class of privileged structural motifs, which found widespread use in medicinal chemistry. However, the synthetic access to fluoroalkenes was much underdeveloped with previous reported methods suffering from either low step economy or harsh reaction conditions. Here we present a Rh(III)-catalysed tandem C-H/C-F activation for the synthesis of (hetero)arylated monofluoro...
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9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp(3))-H and C(sp(2))-H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically controlled tri- and tetrasubstituted acrylic acids.
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ژورنال
عنوان ژورنال: Madridge Journal of Novel Drug Research
سال: 2019
ISSN: 2641-5232
DOI: 10.18689/mjndr-1000117